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Effect of UR-5269 on progression of EAE. WT mice were immunized with MOG(35–55) to actively induce EAE and monitored. After determining the onset of EAE, mice immediately received oral daily administration of vehicle (white circles) or UR-5269 (30 mg/kg, closed circles). A, clinical score of mice with or without UR-5269 treatment. B, body weight of mice with or without UR-5269 treatment.
