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Modulated cytokine production in TLR9 R892W primary B cells. Secretion of IL-10 (A) and IL-6 (B) measured by ELISA in supernatants (in pg/ml) of CD19-enriched primary B cells stimulated with CpG-ODN 2006 (Type B ODN; 0.1, 1 and 10 μm, left panels) or R848 (0.01, 0.1, and 1 μm, right panels) for 48 h. NON, non-stimulated (media only). One of two representative experiments done in duplicate. The error bars represent the standard error of the mean.
