FIGURE 1.

Fluorescence increases after bleaching in the outer and inner segment of isolated rod photoreceptors from mice lacking Rdh12 (A) or Rdh8 (B). The bars are 5 μm. IR, infrared images of the cells. Fluorescence images of the cells (excitation, 360 nm; emission, >420 nm), before (dark) and at different times after bleaching, are shown. The particular fluorescence excitation filter was used to allow comparison with previously reported results from different species including mouse. All of the images are shown with the same intensity scaling. The experiments were done at 37 °C.