Table 2. The area under the ROC curve analysis for distinguishing different diagnosis groups.

Gene Name	Case/Control	Cutoff value	AUC	(95% CI)	Sensitivity	(95% CI)	Specificity	(95% CI)
DBC1	CIN2+/CIN1−	0.97	0.45	(0.51–0.38)	0.57	(0.48–0.66)	0.45	(0.39–0.52)
	CIN3+/CIN2−	5.09	0.60	(0.53–0.68)†	0.37	(0.27–0.48)	0.83	(0.78–0.88)
	SCC/SCC−	13.60	0.73	(0.57–0.74)‡	0.44	(0.28–0.59)	0.94	(0.92–0.97)
ZNF582	CIN2+/CIN1−	0.62	0.78	(0.73–0.84)‡	0.63	(0.54–0.72)	0.85	(0.80–0.90)
	CIN3+/CIN2−	0.62	0.82	(0.76–0.87)‡	0.70	(0.60–0.79)	0.82	(0.76–0.87)
	SCC/SCC−	3.77	0.87	(0.83–0.93)‡	0.77	(0.64–0.90)	0.90	(0.86–0.93)

Abbreviation: ROC, the receiver operation characteristics; AUC, the area under the ROC curve; CI, confidence interval; CIN2, cervical intraepithelial neoplasia type 2; CIN3, cervical intraepithelial neoplasia type 3; SCC, squamous cervical carcinoma; +, the descriptive and worse diagnosis; −, the better diagnosis. DBC1, deleted DNA in bladder cancer 1; ZNF582, Krüppel-type zinc finger 582.

^† P-value <0.01 obtained using the Mann-Whitney U test.

^‡ P-value <0.001 obtained using the Mann-Whitney U test.