Figure 3. AnnexinV- and Cleaved Caspase3-staining after high-dose TKI pulse-exposure.

To confirm results obtained with propidium iodide staining, AnnexinV-PE staining (A) and Cleaved Caspase3-Alexa488 staining (B) of Ba/F3-BCR-ABL cells was performed at 24 hours after HD-TKI pulse-exposure using either imatinib or dasatinib as indicated followed by repetitive wash-out as described in Figure 2 . Experiments were performed in triplicate and one representative experiment is shown.