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. 2012 Jul 16;7(7):e41073. doi: 10.1371/journal.pone.0041073

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Bigford et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(NY), SCI young (SCIY), naïve aged (NO) and SCI aged (SCIO) mice. Quantification of mRNA expression levels show that FIAF is significantly increased in SCIY, NO and SCI O animals compared to NY control. SCIY and SCIO are also significantly increased when compared to NO (A). Rstn mRNA levels are significantly increased in SCIY, NO and SCIO animals compared to NY control. NO and SCIO are also significantly increased when compared to SCIY (B). LepRb mRNA levels are significantly reduced in SCIY, NO and SCIO when compared to NY control (C). SOCS3 mRNA levels are significantly greater in SCIY, NO and SCIO when compared to NY control (D). Statistics are according to data analysis methods described. p≤0.05. n = 5 for each group.