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. 2012 Jul 16;7(7):e41073. doi: 10.1371/journal.pone.0041073

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Bigford et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(NY), SCI young (SCIY), naïve aged (NO) and SCI aged (SCIO) mice. IRE1 phosphorylation, PERK phosphorylation and eIF2α phosphorylation are each significantly increased in SCIY, NO and SCIO when compared to the NY control. IRE1^Total, PERK^Total, and eIF2α^Total were used as internal standards. Statistics are according to data analysis methods described. p≤0.05. n = 8 for each group.