Table 1. A comparison of the p53 and phosphorylated lid interactions with MDM2.

P53residue	MDM2 residue hydrogenbond contact	MDM2 residue hydrophobic contact	Lid residue	MDM2 residue hydrogenbond contact	MDM2 residue hydrophobic contact
E17	K94		pS17	K94,H73
F19	Q72	I61,M62,Y67,V75	Q18	Q72
L22		V93	I19		M62,V93
W23	L54	L57,G58,I61,V93	P20		L54,V93,I99
L26		L54,H96,V93	A21	H96,R97
P27		M50,L54,Y100	S22	R97
E28	K51		E23	K51
N29	Y100,Y104		Q24	M50,Y100,Y104
			E25	K51