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. 2012 Jul 16;7(7):e40982. doi: 10.1371/journal.pone.0040982

Figure 5. Conserved synteny dot plots derived from the Synteny Database [17].

Figure 5

(A–C) Conserved synteny dot plots derived from the Synteny Database [17]. (A) The zebrafish AgRP2 region on Dre 2 (red box) shares conserved syntenies with neither the zebrafish ASIP1 region (Dre 6) nor with the human ASIP region (Hsa 20). (B) The AgRP2 and ASIP2 regions in medaka and other teleosts share conserved synteny with each other and with a region on human Hsa10, including several AgRP2- and ASIP2-neighboring genes. (C) Analysis of the human genome shows that the AgRP region on Hsa16 shows more paralogous connections to the inferred ASIP2 region on Hsa 8 than to the ASIP region on Hsa 20 (183 vs. 82 genes, respectively, not restricting Y-axis chromosomal regions).