Table 6. Stepwise regression analyses with indices of vascular function as dependent variables, and demographic and biochemical data as independent variables in the whole group of PHPT patients and controls.
Variable | Model for AIx | Model for PWVao | Model for IMTcca | Model for IMTrad | Model for IM-GSM | |||||
R2 = 0.58, p<0.001 | R2 = 0.37, p<0.001 | R2 = 0.29, p<0.001 | R2 = 0.07, p<0.05 | R2 = 0.18, p<0.001 | ||||||
β | p-value | β | p-value | β | p-value | β | p-value | β | p-value | |
Age, years | 0.65 | <0.001 | 0.27 | <0.05 | 0.39 | <0.001 | – | – | – | – |
Gender | 0.29 | <0.001 | – | – | – | – | – | – | – | – |
SBP, mmHg | – | – | 0.44 | <0.001 | 0.26 | <0.05 | 0.28 | <0.05 | – | – |
Height, cm | – | – | – | – | – | – | – | – | 0.37 | <0.01 |
Weight, kg | – | – | – | – | – | – | – | – | −0.63 | <0.001 |
P-PTH | – | – | – | – | – | – | – | – | – | – |
S-Ca++ | – | – | – | – | – | – | – | – | – | – |
P-Phosphate | −0.21 | <0.01 | – | – | – | – | – | – | – | – |
S-25-OH-D | – | – | – | – | – | – | – | – | – | – |
AIx = augmentation index, PWVao = aortic pulse wave velocity, IMTcca = intima media thickness in both left and right common carotid artery, IMTrad = intima media thickness in right radial artery, IM-GSM = intima media grayscale median in both left and right common carotid artery, SBP = systolic blood pressure, PTH = parathyroid hormone, P = plasma, S = serum, S-Ca++ = ionized calcium, PTH = parathyroid hormone, S-25-OH-D = 25 hydroxyvitamin D.