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. 2012 Jul 16;7(7):e40957. doi: 10.1371/journal.pone.0040957

Figure 2. Ultrastructural assessment of autophagic changes in the trophoblast layer of placentas from pregnancies complicated by IUGR and PE+IUGR.

Figure 2

Electron micrographs illustrating autophagic vacuoles in the trophoblast layer of the placenta from women with IUGR (a) and PE+IUGR (b, c). These autophagic vacuoles contain intracytoplasmic organelles, such as mitochondria (insets). In addition, loss of mitochondrial integrity (b) and dilatation of cis-ternae of rough endoplasmic reticulum (c) were noted in PE+IUGR placentas. Scale bar  = 1 µm and 500 nm in insets (a, c) and 250 nm and 500 nm in inset (b).