Table 6. Comparisons of Bayley III scores after adjusting for confounders among 4 dioxin groups.
Percentile of PCDDs/Fs-TEQ (pg/gfat) | <25 | 25–50 | 50–75 | ≥75 | |||||||||||||
Gender | Domain | Mean | SE | Mean | SE | p | Mean | SE | p | Mean | SE | p | |||||
Boys | N | 30 | 37 | 28 | 25 | ||||||||||||
Cognitive | Total | cs | 93.0 | 2.3 | 95.2 | 2.0 | 95.1 | 2.3 | 87.2 | 2.6 | b,c | ||||||
Language | Total | cs | 96.1 | 1.2 | 98.4 | 1.0 | 96.7 | 1.2 | 94.0 | 1.3 | b | ||||||
Reseptive com | ss | 8.4 | 0.3 | 9.1 | 0.2 | a | 8.5 | 0.3 | 8.4 | 0.3 | |||||||
Expressive com | ss | 10.2 | 0.2 | 10.3 | 0.2 | 10.3 | 0.2 | 9.5 | 0.2 | a,b,c | |||||||
Motor | Total | cs | 101.1 | 2.0 | 102.4 | 1.7 | 101.1 | 2.0 | 96.9 | 2.2 | |||||||
Fine motor | ss | 8.8 | 0.3 | 9.3 | 0.3 | 8.6 | 0.3 | 7.9 | 0.4 | b | |||||||
Gross motor | ss | 11.4 | 0.5 | 11.4 | 0.4 | 11.7 | 0.5 | 11.0 | 0.5 | ||||||||
Girls | N | 22 | 15 | 24 | 28 | ||||||||||||
Cognitive | Total | cs | 95.0 | 3.0 | 100.2 | 3.3 | 93.8 | 2.6 | 91.1 | 2.5 | b | ||||||
Language | Total | cs | 98.3 | 1.7 | 97.0 | 1.8 | 95.7 | 1.4 | 95.3 | 1.4 | |||||||
Reseptive com | ss | 8.9 | 0.4 | 8.5 | 0.4 | 8.4 | 0.3 | 8.4 | 0.3 | ||||||||
Expressive com | ss | 10.5 | 0.3 | 10.5 | 0.3 | 10.2 | 0.3 | 10.0 | 0.3 | ||||||||
Motor | Total | cs | 105.0 | 2.6 | 106.6 | 2.8 | 101.6 | 2.3 | 101.6 | 2.2 | |||||||
Fine motor | ss | 9.9 | 0.5 | 10.2 | 0.5 | 9.2 | 0.4 | 9.0 | 0.4 | ||||||||
Gross motor | ss | 11.7 | 0.5 | 11.9 | 0.5 | 11.2 | 0.4 | 11.5 | 0.4 |
a: p<0.05 as compared with <25 percentile group, b: p<0.05 as compared with 25–50 percentile group, c: p<0.05 as compared with 50–75 percentile group.
N: number of subjects, Mean: adjusted mean, SE: standard error, p: p-value.
cs: composite score, ss: scale score, com: communication.
Confounders: parity (primipara or not), maternal age, weight, educational period (years), alcohol drinking during pregnancy (yes/no), family income, family smoking (yes/no), gestational weeks, infant age (days) on the day of each examination, and location difference (TK or ST hospital).
Note: Bayley III test could not be performed for 1 girl.