TABLE 1.

Results of the Comparison of Amplification Between OPN5 and 6p21.2 Genes

	>2		>3
	OPN5		OPN5
	2/573 (0.3%)	p, Chi-sq	0	p, Fisher
BTBD9	9/530 (1.7%)	2.43E-02	2/530 (0.4%)	1.42E-01
GLO1	49/536 (8.4%)	2.59E-11	14/577 (2.4%)	2.10E-04
DNAH8	30/568 (5.0%)	9.70E-07	5/595 (0.8%)	2.85E-02
GLP1R	26/532 (4.7)	3.41E-06	7/551 (1.3%)	7.16E-03
C6orf64	16/589 (2.6%)	1.34E-03	3/602 (0.5%)	9.15E-02
KCNK5	15/557 (2.6%)	1.45E-03	2/570 (0.3%)	1.58E-01
KCNK17	26/520 (4.8%)	1.32E-06	5/541 (0.9%)	2.19E-02
KCNK16	11/546 (2.0%)	1.02E-02	3/554 (0.5%)	1.33E-02
C6orf102	7/576 (1.2%)	9.90E-02	2/586 (0.3%)	1.63E-01
DAAM2	8/598 (1.3%)	6.83E-02	3/604 (0.5%)	5.18E-02

In this table the frequencies of amplification (for threshold of >2-fold and >3-fold) of genes mapping to the amplicon on 6p21.2 are listed together with the statistical significance of the difference between amplification frequencies of OPN5 and respective genes. P-values significant after Benjamini-Hochberg correction with a FDR of 10% are indicated in bold. The amplification frequencies were calculated as ratios of the number of samples with amplification confirmed in two independent experiments and the total number of informative samples.