Table 1.
gene name | gene abbreviation | rs | ANOVA p-value | Putative Mechanistic Role |
---|---|---|---|---|
Semaphorin 6A | SEMA6A | rs154576 | 2.03E-07 | LRAM |
microfibril-associated protein 4 | MFAP4 | rs6587082 | 9.18E-05 | ECM |
Fibrinogen C domain containing 1 | FibCD1 | rs12343454 | 3.27E-04 | PB |
Kallmann syndrome 1 | KAL1 | rs12007434 | 7.50E-04 | APG |
galanin-like peptide | GALP | rs16987032 | 1.02E-03 | CHP |
BH-protocadherin | PCDH7 | rs11935515 | 1.41E-03 | ECM, EDMW |
Fibulin5 | FBLN5 | rs741198 | 1.42E-03 | ECM |
Slit homolog 3 | SLIT3 | rs11134534 | 1.55E-03 | LRAM |
Marapsin-2 | MPN2 | rs12079887 | 1.76E-03 | EDMW |
Cub and Sushi Multiple Domains-1 | CsmDI | rs6986644 | 1.93E-03 | LRAM |
Roundabout receptor 1 | ROBOI | rs498805 | 2.24E-03 | LRAM |
Mitogen-activated protein kinase | MAPK8 | rs7075976 | 5.13E-03 | EDMW |
Secreted modular calcium-binding protein-2 | SMOC2 | rs747994 | 5.20E-03 | ECM, MF |
Longevity assurance gene 4 | Lass4 | rs11666866 | 5.64E-03 | APG, CHP |
CD99-Like 2 | cd99L2 | rs2142003 | 9.04E-03 | LRAM |
Insulin-like Growth Factor 1 Receptor | IGF1R | rs11633294 | 1.31E-02 | EDMW |
Grb2-associated binder 2 | GAB2 | rs2450129 | 2.37E-02 | LRAM |
Matrix metalinoproteinase 3 | MMP3 | rs522616 | 2.78E-02 | ECM |
Fibroblast growth factor 1 | FGF1 | rs2299020 | 2.93E-02 | EDMW |
Fibrillin-2 | FBN2 | rs27855 | 3.38E-02 | ECM |
A disintegrin and metalloprotease 12 | ADAM12 | rs17154587 | 4.11E-02 | ECM, EDMW |
Matrillin-2 | MTR2 | rs4360265 | 6.76E-02 | ECM |
Tribbles homolog 1 | TribI | rs2235108 | 1.53E-01 | APG, EDMW |
APG- antimicrobial peptides/glycopeptides, CHP- cutaneous hydration and permeability, ECM- extracellular matrix formation/integrity/remodeling, EDMW- epidermal development/maintenance/wound repair, LRAM- leukocte recruitment/activation/migration, MF- melanocyte function, PB- parasite binding