TABLE 1.

Class 1 and 2 Properties

Class 1 (Driver)	Class 2 (Modulator)
Activates only ionotropic receptors	Activates metabotropic receptors
Synapses show paired-pulse depression (high p)†	Synapses show paired-pulse facilitation
Large EPSPs	Small EPSPs
Less convergence onto target	More convergence onto target
Thick axons	Thin axons
Large terminals on proximal dendrites	Small terminals on distal dendrites
Dense terminal arbors	Delicate terminal arbors

^†See text for slight variation called “Class 1C”