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IC50 values for p-XSC in combination with varying doses of rapamycin (0.1 - 1000 nM) and IC50 values for rapamycin in combination with single doses of p-XSC (0.625 - 5 μM) in C4-2 cells treated for 48 hr. MTT assays were used to generate the dose curves from which the IC50 values were calculated.
| [Rapa] (nM) | IC50 p-XSC (μM) | [p-XSC] (μM) | IC50 Rapa (nM) |
|---|---|---|---|
| 0 | 7.2 | 0 | 49000 |
| 0.1 | 5.9 | 0.625 | 1400 |
| 1 | 3.5 | 1.25 | 570 |
| 10 | 3.3 | 2.5 | 560 |
| 100 | 2 | 5 | 0.2 |
| 1000 | 1.3 |
