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. Author manuscript; available in PMC: 2013 Jul 13.
Published in final edited form as: Mol Cell. 2012 May 31;47(1):50–60. doi: 10.1016/j.molcel.2012.04.028

Figure 2. Survival of WT and deletant S. pombe strains and persistence of O6-MeG in DNA after exposure to MNNG.

Figure 2

(A–F) MNNG-sensitivity measured by clonogenic survival assays for WT (GM1) and deletants: atl1 (GM3)

(A) swi10 (OL455), atl1 swi10 (GM48)

(B) rhp7 (GM56), atl1 rhp7 (GM61)

(C) rhp23 (GM50), atl1 rhp23 (GM100)

(D) rhp41 (TM4), atl1 rhp41 (GM46)

(E) rhp26 (GM51), rhp7 (GM56), rhp7 rhp26 (GM121)

(F) rad50 (GM11), atl1 rad50 (GM15)

(G) The amount of O6-MeG in DNA at various times after 10 min exposure to MNNG (10 μg/mL).

Values are the mean of triplicate or quadruplicate treatments and error bars represent standard error of the mean.