Table 1.
AGTR1 htSNP genotype frequency differences by diagnostic cohort
| htSNP | Location | SNP | Depressed | Nondepressed | Wald χ2 | P value |
|---|---|---|---|---|---|---|
| rs2638363 | Intron 1 | A/G | GG: 68.3% (168) AA / AG: 31.7% (78) |
GG: 66.1% (74) AA / AG: 33.9% (38) |
0.1460 | 0.7024 |
| rs10935724 | Intron 1 | A/C | AA: 52.0% (128) CC / AC: 48.0% (118) |
AA: 41.2% (47) CC / AC: 58.8% (67) |
3.89 | 0.0487 |
| rs1492103 | Intron 2 | C/T | TT: 69.6% (172) CC / CT: 30.4% (75) |
TT: 69.4% (77) CC / CT: 30.6% (34) |
0.00 | 0.9727 |
| rs718858 | Intron 2 | C/T | CC / CT:27.8% (68) TT:72.2% (177) |
CC / CT: 35.1% (40) TT: 64.9% (74) |
1.96 | 0.1621 |
| rs12721331 | Intron 2 | C/T | TT: 89.9% (222) CC / CT: 10.1% (25) |
TT: 79.8% (91) CC / CT: 20.2% (23) |
6.98 | 0.0082 |
| rs2675511 | Intron 2 | A/G | GG / AG: 47.4% (117) AA: 52.6% (130) |
GG / AG: 43.9% (50) AA: 56.1% (64) |
0.33 | 0.5678 |
| rs389566 | Intron 2 | A/T | AA / AT:46.4% (117) TT: 53.6% (135) |
AA / AT:46.1% (53) TT: 53.9% (62) |
0.00 | 0.9585 |
| rs12695902 | Intron 3 | A/G | GG / AG: 16.5% (41) AA: 83.5% (208) |
GG / AG: 21.7% (25) AA: 78.3% (90) |
1.51 | 0.2190 |
| rs385338 | Intron 3 | C/G | CC / CG: 33.9% (83) GG: 66.1% (162) |
CC / CG: 33.3% (38) GG: 66.7% (76) |
0.05 | 0.8317 |
| rs5182 | Exon 5 | C/T | CC / CT: 78.9% (198) TT: 21.1% (53) |
CC / CT: 79.1% (91) TT: 20.9% (240) |
0.00 | 1.0000 |
Data presented as % (N) for each diagnostic group. Statistical results presented from logistic regression models predicting diagnostic cohort as the dependent variable, including age and sex as independent covariates.