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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Brain Behav Immun. 2012 May 29;26(6):996–1005. doi: 10.1016/j.bbi.2012.05.012

Fig. 4.

Fig. 4

(A) The effects of chronic vs. acute stress on plasma IL-12 levels. Both acute stress (10 hrs of wet-cage exposure) and chronic stress (two weeks of daily alternating stress paradigms) reduced plasma IL-12 levels. Seven days of chronic stress had a greater impact than one day of acute stress (see week 1). However, 7 days of chronic stress reduced IL-12 levels greater than 14 days of stress. * indicates a significant difference from control levels within each week. # indicates a significant difference between chronic and acute groups within each week. Data are presented as mean + SEM. (B) Schematic representation of the design and procedure of exp. 4. The control group was not subjected to stress, the acute group was subjected to 10 hrs of stress on day 6, and the chronic stress group was subjected to two weeks of alternating stress paradigms. Blood was withdrawn via the tail every week from all animals.