Fig. 3.
Liver GPx activity alterations when SAMe was administered 1 h after APAP overdose. C57Bl/6 mice were randomly divided into Veh (water), SAMe (1.25 mmol/kg), APAP (250 mg/kg), and SAMe administered 1 h following APAP (S + A). Livers were collected 2 and 4 h following APAP overdose. All values represent mean ± S.E.M. Each group represents 5 mice with superscripts denoting statistically significant differences (p<0.05).