Table 1.
Baseline Characteristics of Normal vs. BoPAP vs. Resting PH groups who underwent RHC
| TOTAL(N=206) | NORMAL(N=35) | BORDERLINE (N=28) | Resting PH (N=143) | |||||
|---|---|---|---|---|---|---|---|---|
| Mean(SD) | Median | Mean(SD) | Median | Mean(SD) | Median | Mean(SD) | Median | |
| Age, years | 57.2(11.6) | 58.0 | 55.7(12.6) | 57.0 | 54.8 (10.4) | 55.0 | 58.0(11.5) | 59.0 |
| Female, N(%) | 171(85.1) | 28(80.0) | 24(85.7) | 119(85.6) | ||||
| Scleroderma subtype, N(%) | ||||||||
| Limited | 129(62.6) | 22(62.9) | 16(61.5) | 91(62.8) | ||||
| Diffuse | 66(32.0) | 11(29.7) | 9(34.6) | 46(31.7) | ||||
| Unclassified | 11(5.3) | 2(5.4) | 1(3.9) | 6(5.5) | ||||
| Disease Duration (yrs) | ||||||||
| From onset of Raynaud phenomenon | 11.6(10.3) | 8.5 | 10.7(8.5) | 7.8 | 8.6(6.1) | 7.3 | 12.4(11.2) | 9.0 |
| From onset of non-Raynaud symptom | 8.7(7.3) | 6.7 | 7.8(5.4) | 6.8 | 8.1(6.0) | 6.2 | 9.1(8.0) | 6.7 |
| From first SSc diagnosis | 7.1 (8.1) | 4.5 | 5.1(4.5) | 3.6 | 5.9(6.2) | 3.3 | 7.8(9.0) | 5.3 |
| Race, N(%) | ||||||||
| Caucasian | 140(69.6) | 22(62.9) | 17(60.7) | 101(73.2) | ||||
| Hispanic | 15(7.5) | 5(14.3) | 2(7.1) | 8(5.8) | ||||
| African-American | 37(18.4) | 6(17.1) | 7(25.0) | 24(17.4) | ||||
| Other | 9(4.5) | 2(5.7) | 2(7.1) | 5(3.6) | ||||
| HAQ-DI score(0–3) | 0.9(0.8) | 0.8 | 0.8(0.8) | 0.5 | 0.7(0.6) | 0.6 | 1.0(0.8) | 1.0 |
| VAS Breathing score(0–3) | 1.2(0.9) | 1.0 | 0.8(0.7) | 0.6 | 0.9(0.9) | 0.5 | 1.3(0.9) | 1.5 |
| VAS Raynaud’s score(0–3) | 0.6(0.8) | 0.3 | 0.6(0.7) | 0.4 | 0.4(0.7) | 0.1 | 0.7(0.8) | 0.3 |
| VAS Finger ulcers score(0–3) | 0.5(0.8) | 0.1 | 0.4(0.7) | 0.1 | 0.3(0.6) | 0 | 0.5(0.8) | 0.1 |
| VAS Overall score(0–3) | 1.2(0.8) | 1.2 | 1.0(0.8) | 1.0 | 0.9(0.8) | 0.8 | 1.4(0.8) | 1.4 |
| UCSD score(0–5) | 1.6(1.1) | 1.5 | 1.2(0.8) | 1.2 | 1.4(1.1) | 1.1 | 1.8(1.2) | 1.7 |
| SF-36 PCS | 30.7(10.8) | 28.4 | 33.6(9.6) | 31.1 | 36.8(13.2) | 37.9 | 28.5(9.9) | 27.5 |
| SF-36 MCS | 48.1(11.3) | 49.6 | 49.6(12.8) | 54.0 | 50.3(9.4) | 49.9 | 47.2(11.2) | 49.0 |
p> 0.05 for all comparisons; HAQ-DI: Health Assessment Questionnaire – Disease Index; VAS: Visual Analogue Scale, UCSD: University of California at San Diego; SF-36: Short form 36; PCS: Physical Component Summery; MCS: Mental Component Summery