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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Virus Res. 2012 May 23;167(2):273–284. doi: 10.1016/j.virusres.2012.05.010

Figure 5.

Figure 5

HSV-2 infection specifically affects STAT2 protein levels in early phase-inhibited (A) but not late phase-inhibited (C) 293α/β cells. HSV-2 infected 293A cells were analyzed by western blot for levels of STAT1, STAT2, IRF9, HSV gB and actin expression at 0, 4, 8, and 16 hpi. (B) In early phase-inhibited 293A cells, abrogation of HSV-2 DNA replication by PAA does not affect HSV-2-mediated loss of STAT2 expression. The same results were observed with acyclovir treatment (data not shown). (C) In late phase-inhibited 293α/β cells, STAT2 protein levels are unaffected by HSV-2 infection.