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. Author manuscript; available in PMC: 2013 Aug 10.
Published in final edited form as: J Mol Biol. 2012 Apr 24;421(2-3):378–389. doi: 10.1016/j.jmb.2012.04.017

Figure 2. The anti-amyloidogenic activity of sNUCB1 is Ca2+-dependent.

Figure 2

The aggregation of hIAPP was monitored in the presence of equimolar sNUCB1. In the absence of Ca2+, sNUCB1 effectively inhibit hIAPP fibril formation when added at T = 0. When excess Ca2+ (3 mM) is present in the reaction mixture, sNUCB1 does not inhibit hIAPP fibril formation.