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SATB1 protects gastric cancer cells from VCR-induced apoptosis. The cells were incubated with 1 μg/ml VCR for 36 h and the apoptotic index was calculated based on flow cytometry and Annexin V/PI staining. The apoptotic index was 19.8, 35.0, 8.6, 10.6, 16.8 and 4.7%, for SGC7901, SGC7901-siRNASATB1, SGC7901-SATB1, SGC7901/VCR, SGC7901/VCR-siRNASATB1 and SGC7901/VCR-SATB1 cells, respectively. SATB1, special AT-rich sequence binding protein 1; VCR, vincristine; PI, propidium iodide.
