Table II.
Cell lines | Accumulation | Retention |
---|---|---|
SGC7901 | 74.48±5.54 | 52.71±6.59 |
SGC7901-siRNASATB1 | 86.32±4.48a | 33.75±3.41a |
SGC7901-SATB1 | 64.25±3.60 | 33.75±3.41 |
SGC7901/VCR | 28.14±1.58c | 15.85±1.70c |
SGC7901/VCR-siRNASATB1 | 33.56±5.87 | 18.97±1.20 |
SGC7901/VCR-SATB1 | 20.56±2.31b | 8.54±1.05b |
The values of VCR accumulation and retention were measured by flow cytometry and presented as the mean ± SD of three independent experiments.
P<0.05 and
P<0.05 vs. their respective control cells.
P<0.01, SGC7901 vs. SGC7901/VCR cells.
SATB1, special AT-rich sequence binding protein 1; VCR, vincristine.