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. 2012 Jul 17;3:208. doi: 10.3389/fimmu.2012.00208

Table 1.

Reported involvement of MDSC in transplantation.

Phenotype Species Models Mechanisms Reference
CD3-ClassII-CD11b+CD80/86+ Rat Renal transplant tolerance Accumulation; iNOS Dugast et al. (2008)
Gr-1+CD11b+ Mouse GVHD inhibition Altered Ag processing by DC Ghansah et al. (2004), Paraiso et al. (2007)
CD115+Gr-1+F4/80+ Mouse GVHD prevention IL-10; iNOS Zhou et al. (2010)
CD11b+Ly6GlowLy6C+ Mouse GVHD inhibition Arg1 Highfill et al. (2010)
Gr-1+CD11b+ Mouse Skin allograft; long-term survival iNOS Adeegbe et al. (2010)
Gr-1+CD11b+ Mouse Skin allograft; long-term survival Arg1 Zhang et al. (2008)
Gr-1+CD11b+ IL-4Rα+ Mouse Islet allograft tolerance C/EBPβ factor; Arg1; iNOS Marigo et al. (2010)
Gr-1+CD115+CD11b+ Mouse Cardiac transplant tolerance IFN-γ-dependent pathways Garcia et al. (2010)
CD33+HLA-DR-CD11b+CD14+/- Human Renal transplantation Accumulation Hock et al. (2012)