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Effect of RGZ on insulin tolerance test (ITT). At 12 weeks of age, insulin was administered at 1 unit/kg body weight subcutaneously after an overnight fast. Glucose was assayed at time = 0 (baseline), 15, 30, 60, 120, and 180 minutes following insulin administration. There were no significant differences in serum glucose values between the treated and control groups during any of the time points of the ITT (P > 0.05).
