(b)
| Sequencers | 454 GS FLX | HiSeq 2000 | SOLiDv4 | 3730xl |
|---|---|---|---|---|
| Instrument price | Instrument $500,000, $7000 per run | Instrument $690,000, $6000/(30x) human genome | Instrument $495,000, $15,000/100 Gb | Instrument $95,000, about $4 per 800 bp reaction |
| CPU | 2* Intel Xeon X5675 | 2* Intel Xeon X5560 | 8* processor 2.0 GHz | Pentium IV 3.0 GHz |
| Memory | 48 GB | 48 GB | 16 GB | 1 GB |
| Hard disk | 1.1 TB | 3 TB | 10 TB | 280 GB |
| Automation in library preparation | Yes | Yes | Yes | No |
| Other required device | REM e system | cBot system | EZ beads system | No |
| Cost/million bases | $10 | $0.07 | $0.13 | $2400 |