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. 2000 May 23;97(11):5684–5686. doi: 10.1073/pnas.97.11.5684

Figure 1.

Figure 1

Stress-responsive eIF2α protein kinases. Consistent with its signal transducing role, PKR responds to a variety of different stimuli, including growth factor (GF), interleukin 3 (IL-3), tumor necrosis factor α (TNF-α), and altered calcium (Ca2+) levels, heat shock, and bacterial lipopolysaccharide (LPS). AA, amino acid; dsRNA, double-stranded RNA; ER, endoplasmic reticulum. See text for further details.