Table 1. Experimental Design.
| Cohort | Behavioral assessment |
Neuroanatomical and biochemical assessment
|
||
|---|---|---|---|---|
| Staining for IgG deposits | Histological assessment | Biochemical assessment | ||
| 1 | Activity; plus maze; induced-grooming under vehicle or paroxetine; food manipulation | 21 GAS ratsa 17 control ratsa | All rats | |
| 2 | Food manipulation under vehicle or haloperidol; beam walking | 14 GAS rats 17 control rats | 7 GAS ratsb 6 control ratsb | |
a
Sections of 14 and 40 μm were taken alternately from the same animals for the detection of IgG deposits and histology, respectively.
b
These rats were not administered haloperidol.