Table 1.
entry | R | bromide | sulfinamide | yield (%)a | drb |
---|---|---|---|---|---|
1 | CO2Me | 5a | 11a | 55 | >6:1 |
2 | CO2Et | 5b | 11b | 50 | >6:1 |
3 | CH2OTBS | 5c | 11c | 85 | 4:1 |
4 | CH2OPMB | 5d | 11d | 0 | - |
5 | CH2OH | 5e | 11e | 31 | 3:1 |
entry | R | bromide | sulfinamide | yield (%)a | drb |
---|---|---|---|---|---|
1 | CO2Me | 5a | 11a | 55 | >6:1 |
2 | CO2Et | 5b | 11b | 50 | >6:1 |
3 | CH2OTBS | 5c | 11c | 85 | 4:1 |
4 | CH2OPMB | 5d | 11d | 0 | - |
5 | CH2OH | 5e | 11e | 31 | 3:1 |