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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Arch Neurol. 2012 Mar;69(3):380–384. doi: 10.1001/archneurol.2011.1060

Table 2.

Use of statins and PD risk in the Health Professionals Follow-up Study and the Nurses’ Health Study (1994-2006)

Use of statins
no yes P value
HPFS
    Case # 282 24
    Age- and smoking- adjusted RR 1(ref) 0.79(0.52, 1.20) 0.27
    Multivariate RR 1(ref) 0.78 (0.50, 1.22) 0.27
NHS
    Case # 311 27
    Age- and smoking- adjusted RR 1(ref) 0.74 (0.50, 1.11) 0.14
    Multivariate RR 1(ref) 0.70 (0.46, 1.07) 0.10
Pooled RR 1(ref) 0.74 (0.54, 1.00) 0.049

1Adjusted for age (in months), smoking status (never smoker, past smoker, current smoker with 1-14 cigarettes/d, or current smoker with ≥ 15 cigarettes/d), BMI (<23, 23-24.9, 25-26.9, 27-29.9, or ≥30 kg/m2), intake of caffeine (quintiles), lactose (quintiles), and alcohol (none, 1-4.9, 5-9.9, 10-14.9, or ≥15 g/d for women; none, 1-9.9, 10-19.9, 20-29.9, or ≥30 g/d for men), physical activity (quintiles), use of ibuprofen (yes/no), duration of hypercholesterolemia (years) and presence of coronary heart disease, hypertension, and diabetes (yes/no for each).