Table 3. RRs and Heterogeneity Results for the Genetic Contrasts of Arg389Gly and Ser49Gly β1 AR Polymorphisms for HF.

Polymorphism	Ethnicity	RR (95% CI)	Studies	I2, %	P h	Overall effect, P
Arg389Gly
Gly vs. Arg	All	1.01 (0.95, 1.08)	14	52	0.01	0.66
	Asian	1.10 (1.01, 1.19)	4	26	0.25	0.03
	White	0.94 (0.89, 1.00)	7	38	0.14	0.06
	Black	1.00 (0.91, 1.10)	2	0	0.5	0.98
Gly389 carrier vs. Arg389Arg	All	1.00 (0.93, 1.08)	14	41	0.05	0.98
	Asian	1.05 (0.95, 1.17)	4	35	0.2	0.31
	White	0.95 (0.88, 1.03)	7	34	0.17	0.19
	Black	0.98 (0.86, 1.12)	2	0	0.84	0.77
Gly389Gly vs. Arg389 carrier	All	1.08 (0.93, 1.24)	14	50	0.01	0.31
	Asian	1.35 (1.16, 1.57)	4	0	0.48	0.0001
	White	0.84 (0.71, 1.00)	7	0	0.46	0.05
	Black	1.05 (0.87, 1.27)	2	50	0.16	0.62
Ser49Gly
Gly vs. Ser	All	1.22 (1.04, 1.43)	8	80	<0.01	0.02
	Sensitivity	1.11 (0.97, 1.27)	6	51	0.07	0.13
	Asian	1.18 (1.06, 1.31)	2	44	0.18	0.003
	White	1.34 (0.95, 1.90)	4	90	<0.01	0.1
Gly49 carrier vs. Ser49Ser	All	1.33 (1.03, 1.72)	8	52	0.04	0.03
	Sensitivity	1.25 (0.94, 1.66)	6	48	0.08	0.12
	Asian	1.24 (0.72, 2.13)	2	64	0.09	0.44
	White	1.48 (0.86, 2.57)	4	72	0.01	0.16
Gly49Gly vs. Ser49 carrier	All	1.24 (0.74, 2.08)	8	81	<0.01	0.42
	Sensitivity	1.03 (0.76, 1.39)	6	0	0.84	0.86
	Asian	1.72 (0.95, 3.12)	2	69	0.07	0.07
	White	1.08 (0.73, 1.62)	4	0	0.76	0.69