Figure 13.Dlx5 genomic structure with 5′flanking region (1100 bp, black line), the non translated region (182 bp, light gray box), whose left border indicates the transcription start site, the □rst exon (355 bp, dark gray box) and a part of the □rst intron. The vertical bars above the horizontal line of the gene indicate the CpGs and the vertical lines labeled with M indicate the MboII restriction sites. Two fragments indicated by light gray arrows and labeled as distal and proximal fragments are used for the “MethylMiner” assay.