Table 1. Expression of genes involved in osteoblastic extra-cellular matrix synthesis by genome wide expression analysis.
| Gene | Co | 1d 1%DMSO |
5d 1%DMSO |
|---|---|---|---|
|
Col1a1 |
1.00 |
1.09 |
1.21 |
|
Col1a2 |
1.00 |
1.10 |
1.18 |
|
Col5a1 |
1.00 |
1.16 |
1.77 |
|
Col5a2 |
1.00 |
1.16 |
1.24 |
|
Plod1 |
1.00 |
1.21 |
1.06 |
|
Plod2 |
1.00 |
1.29 |
2.00 |
|
Plod3 |
1.00 |
1.05 |
1.20 |
|
Lox |
1.00 |
1.04 |
1.39 |
| Mmp13 | 1.00 | 1.82 | 0.12 |
Fold increase of mRNA expression of the genes compared with untreated control cells. Genes up- or downregulated beyond 1.1-fold or 1.5 fold are marked in bright red or dark red, respectively. Genes downregulated beyond 1.1-fold (< 0.91) are marked in green.