Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Radiation induces c-Met expression and radiosensitizes A549 and H460 cells. Treatment of A549 and H460 cells with a single 4-Gy dose of radiation induced c-Met expression starting 30 minutes after the irradiation and persisting for 24 hours (panels A and B). Further, adding MK-8033 to fractionated radiation (4Gy times two separated by 24hrs) reduced colony-forming ability, suggesting that upregulation of c-Met by the first irradiation further sensitized the cells to MK-8033.
