Table 1.
WAS scoring system according to Zhu et al. (1997), with subsequent refinements (Ochs and Thrasher, 2006; Ochs et al., 2009).
| Clinical scores | iXLT | XLT |
WAS |
|||
|---|---|---|---|---|---|---|
| <1 | 1 | 2 | 3 | 4 | 5 | |
| Thrombocytopenia | −/+ | + | + | + | + | + |
| Small platelets | + | + | + | + | + | + |
| Eczema | − | − | (+) | + | ++ | (+)/+/++ |
| Immunodeficiency | − | −/(+) | (+) | + | + | (+)/+ |
| Infections | − | − | (+) | + | +/++ | (+)/+/++ |
| Autoimmunity or malignancy | − | − | − | − | − | + |
Scoring system: −, absent; (+), mild; +, present; ++, present and severe. iXLT, intermittent X-linked thrombocytopenia; WAS, Wiskott–Aldrich syndrome; XLT, X-linked thrombocytopenia.