Figure 7.

Environmental enrichment reverses hypoxia-induced cognitive deficits. Mice were reared in normoxia or hypoxia from P3 to P11 and subsequently in standard or enriched environment from P21 to P35. Behavioral testing was conducted on P35–36. A–C, Results of the Morris water maze. A, The proportion of mice that successfully found the platform in under 60 s, averaged across six trials, during the acquisition phase on the maze. B, The latency to find the platform across trials. C, Probe trial. D, E, Results from the open field test. D, Proportion of distance traveled in the center/total distance traveled. E, Time spent in the center. *, Significance from all other groups; **, significance from NSE and NEn groups, #, HSE and NEn are different from all other groups.