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. Author manuscript; available in PMC: 2012 Jul 18.
Published in final edited form as: Pharm Stat. 2011 May 5;11(1):39–48. doi: 10.1002/pst.493

Table IV.

Overall performance ranks of randomization design-scenarios Weight wI = wR = 1, Sample size = 100.

Rank* G Design (parameter) EB Dn§ MI ET DA** CG†† UI‡‡ UR§§
1 0.253 Big stick(δ = 4) 0.129   2.454   3.999 0.611 0.118 0.558 0.272 0.231
2 0.254 Biased coin with imbalance tolerance (δ = 4, pbias = 0.50) 0.130   2.473   3.999 0.612 0.118 0.559 0.272 0.238
12 0.339 Symmetric extension of Ehrenfest urn design (w = 1, pbias = 0.90) 0.199   3.357   4.458 0.349 0.497 0.590 0.314 0.362
26 0.362 Ehrenfest urn design (w = 10) 0.181   2.221   5.228 0.669 0 0.585 0.384 0.340
46 0.392 Permuted block design (b = 30) 0.196   2.633   5.608 0.635 0.056 0.591 0.418 0.364
85 0.436 Permuted block design (b = 12) 0.285   1.702   3.916 0.574 0.137 0.639 0.265 0.557
103 0.466 Permuted block design (b = 10) 0.307   0   3.620 0.553 0.167 0.654 0.238 0.615
109 0.480 Permuted block design (b = 8) 0.329   1.524   3.272 0.537 0.192 0.662 0.206 0.646
149 0.523 Permuted block design (b = 6) 0.365   1.270   2.830 0.505 0.241 0.680 0.166 0.721
181 0.594 Permuted block design (b = 4) 0.416   0   2 0.448 0.334 0.709 0.091 0.835
255 0.709 Permuted block design (b = 2) 0.500   0   1 0.347 0.5 0.751 0 0.003
57 0.404 Generalized biased coin design (ρ = 5) 0.216   3.040   5.503 0.647 0.010 0.600 0.409 0.399
59 0.407 Variable block design(bmax = 50) 0.199   2.435   5.811 0.631 0.063 0.594 0.437 0.376
79 0.432 Biased coin design (pbias = 0.65) 0.236   2.349   5.490 0.658 0 0.614 0.408 0.455
112 0.490 Random allocation rule 0.116   0   8.207 0.668 0.020 0.558 0.654 0.231
113 0.491 Wei’s UD (w = 1, α = 0, β = 5) 0.122   5.696   8.404 0.684 0 0.543 0.672 0.172
118 0.492 Wei’s adaptive BCD 0.125   5.673   8.415 0.680 0.010 0.544 0.673 0.178
187 0.600 Asymmetric extension of Ehrenfest UD (w = 30) 0.084   7.700 10.317 0.687 0 0.517 0.846 0.066
218 0.658 Truncated binomial design 0.080   0 11.102 0.638 0.079 0.540 0.917 0.162
249 0.707 SR 0.071 10.017 12.019 0.693 0 0.501 1 0.003

Simulation runs = 5000.

*

Only the highest ranking scenario for each design and the most commonly used permuted block designs are listed.

Overall performance measure based on maximum absolute imbalance and correct guess probability.

Probability of exact balance.

§

Standard deviation of final treatment imbalance.

Maximum absolute imbalance.

Entropy of treatment assignment.

**

Proportion of deterministic assignment.

††

Probability of correct guess.

‡‡

Unified scale of treatment imbalance.

§§

Unified scale of allocation randomness.