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Effect of 18α-GA on phosphorylation level of Smad2 and Smad3 in human and rat HSCs. The phosphorylation level of Smad3 was significantly reduced at 24 h and 48 h, while that of phosphorylation of Smad2 remained unchanged. I and III, phosphorylation of Smad2; III and IV, phosphorylation of Smad3. I and III: LX-2; II and IV: CFSC. A: 0 h, B: 24 h; C: 48 h.
