Table 5.
CTLA4 genotype frequencies in single lung lesion patients (N=70) and double lung lesion patients (N=69).
| SNP sites | Genotype | Single lung lesion N (Freq) | Double lung lesion N (Freq) | P value | OR (95% CI) |
|---|---|---|---|---|---|
| +49 | GG | 34 (48.57) | 29 (42.03) | 1 | |
| rs231775 | AA | 11 (15.71) | 9 (13.04) | 0.936 | 0.959 (0.349-2.636) |
| AG | 25 (35.72) | 31 (44.93) | 0.310 | 1.454 (0.705-2.997) | |
| +6230 | GG | 45 (64.29) | 38 (60.32) | 1 | |
| rs3087243 | AA | 4 (5.71) | 6 (9.52) | 0.509 | 1.776 (0.467-6.764) |
| AG | 21 (30.00) | 19 (30.16) | 0.858 | 1.071 (0.503-2.282) | |
| 11430 | GG | 52 (74.29) | 45 (71.43) | 1 | |
| rs11571319 | AA | 1 (1.43) | 4 (6.35) | 0.192 | 4.622 (0.498-42.900) |
| AG | 17 (24.28) | 14 (22.22) | 0.905 | 0.952 (0.422-2.144) |
SNP: single-nucleotide polymorphism; N: number of alleles; Freq: frequency; OR: Odds Ratio (double lung lesion/single lung lesion); 95% CI: 95% Confidence Intervals.