Table 3.
Antifungal activity of chitosan solution and nanoparticles against selected fungi species, n = 3. CS: chitosan; NP: nanoparticles.
| Sample | Particle size | Zeta potential | MIC90 (mg/mL) | |||
|---|---|---|---|---|---|---|
| (nm) | (mV) | C. albicans | F. solani | A. niger | ||
| Amphotericin B (positive control) | — | — | 0.002 | 0.02 | 0.002 | |
| HMW CS solution | — | — | 3 | 3 | 3 | |
| LMW CS solution | 3 | 3 | 3 | |||
| TMC solution | — | — | — | |||
|
| ||||||
| LMW | 174 ± 38.47 | +39 ± 8.56 | 0.25 | 1 | — | |
| CS NP prepared from 1 mg/mL CS | HMW | 210 ± 24.54 | +40 ± 3.16 | 1 | 0.5 | — |
| TMC | 433 ± 79.59 | +37 ± 2.75 | — | — | — | |
|
| ||||||
| LMW | 233 ± 41.38 | +38 ± 1.85 | 0.8572 | 0.8572 | — | |
| Cs NP prepared from 2 mg/mL CS | HMW | 263 ± 86.44 | +52 ± 6.27 | 0.8572 | 0.8572 | 1.7143 |
| TMC | 211 ± 89.26 | +33 ± 4.79 | — | — | — | |
|
| ||||||
| LMW | 255 ± 42.81 | +48 ± 4.78 | 0.6072 | 1.2143 | — | |
| Cs NP prepared from 3 mg/mL CS | HMW | 301 ± 72.85 | +54 ± 5.01 | 0.6072 | 1.2143 | 2.4286 |
| TMC | 297 ± 64.72 | +37 ± 2.52 | — | — | — | |