Table 2.
Atrial pathology of Fontan hearts versus control hearts
RIGHT ATRIUM | p value | LEFT ATRIUM | p value | |||
---|---|---|---|---|---|---|
Fontan (n=47) |
Controls* (n=15) |
Fontan (n=47) |
Controls* (n=8) |
|||
Wall thickness (mm) | 3.0±1.0 (1.7-7.0) | 1.8±0.4 (1.0-2.5) | <0.001 | 2.3±0.6 (1.0-4.0) | 1.8±0.5 (1.0-2.3) | 0.024 |
Fibrosis (%) | 21±10 (7.9-47.4) | 16±5 (9.3-23.9) | NS | 21±9 (6.8-43.2) | 28±8 (18.3-43.0) | NS |
|
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Fibrosis pattern§ | ||||||
Interstitial | 36/40 | 8/13 | NS | 33/40 | 5/8 | NS |
Focal | 1/40 | 0/13 | 4/40 | 1/8 | ||
Mixed | 3/40 | 5/13 | 8/40 | 2/8 |
Control data available for 15 right atrial specimens, but only 8 left atrial specimens
Poor slide quality prevented accurate determination of fibrosis pattern for 7 Fontan and 2 control hearts