TABLE 1.
Effect of ouabain on FasL-induced apoptosis.
% “apoptotic” cells
| ||||
---|---|---|---|---|
0ng/ml FasL | 25ng/ml FasL | 50ng/ml FasL | 100ng/ml FasL | |
- Ouabain | 15.7 ± 1.2 | 31.1 ± 2.2 | 36.0 ± 3.4 | 41.6 ± 2.3 |
+100μM ouabain | 22.4 ± 1.6 | 41.2 ± 1.7* | 49.3 ± 1.2* | 61.9 ± 1.2* |
Results represent the means ± the standard error of five independent experiments. % of apoptotic cells reflects the percentage of shrunken cells determined as shown in Figure 1A. Asterisks indicate statistical significance (at P<0.05) between mean values of control cells (- Ouabain) and ouabain treated cells.