FIGURE 1.

(A) Schematic of the modeling process. Data obtained using experimental biological approaches was used to develop a series of models: Domain Model – explicitly capturing an abstraction of the biological system; Platform Model – detailing how the biological system is implemented as a computer simulation; Simulation Platform – coding the platform model; Results Model – interpretation of simulation results and relationship to biological system. Through use of in silico experimental results model new models and new hypothesis can be developed. (B) To determine if the size and number of PP that form in mice is stochastic, the relative size and location of PP from six adult mice was determined.