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. 2012 Jul 4;8:389–415. doi: 10.4137/EBO.S9743

Table S5.

The between-gene variance in exonic dN explained by the principal components broken down to eleven exon features (upper half); or to six feature categories (lower half).

Var. explained Comp 1 Comp 3 Comp 4 Comp 8 Comp 9 Comp 2 Comp 6 Comp 10 Comp 5 Comp 7 Comp 11
Exon features (Sub)total
17.973 15.941 1.269 0.267 0.207 0.121 0.059 0.050 0.042 0.008 0.005 0.003
ASE/CSE exon type 0.077 0.0457 0.0003 0.0014 0.0001 0.0000 0.0286 0.0002 0.0000 0.0000 0.0000 0.0013
Weighted exon frequency (WEF) 0.091 0.0590 0.0010 0.0016 0.0000 0.0000 0.0285 0.0002 0.0000 0.0000 0.0000 0.0013
Average exonic expression level 2.082 1.5039 0.5183 0.0011 0.0002 0.0583 0.0001 0.0001 0.0001 0.0000 0.0000 0.0000
5′ intron length 0.380 0.2908 0.0022 0.0797 0.0002 0.0000 0.0005 0.0033 0.0000 0.0008 0.0025 0.0000
3′ intron length 0.241 0.1272 0.0042 0.1027 0.0010 0.0010 0.0002 0.0015 0.0000 0.0009 0.0022 0.0000
Exon length 2.583 2.1880 0.3275 0.0021 0.0105 0.0511 0.0004 0.0013 0.0011 0.0006 0.0000 0.0000
G+C content 0.206 0.0005 0.1197 0.0553 0.0029 0.0075 0.0000 0.0175 0.0006 0.0022 0.0000 0.0000
Exon duplicability 0.204 0.1647 0.0072 0.0040 0.0000 0.0000 0.0002 0.0242 0.0000 0.0038 0.0000 0.0000
% solvent-accessible amino acid residues 3.239 2.9830 0.1619 0.0167 0.0622 0.0031 0.0003 0.0017 0.0104 0.0001 0.0000 0.0000
% intrinsically disordered regions 4.933 4.8077 0.0961 0.0021 0.0012 0.0002 0.0002 0.0000 0.0252 0.0000 0.0000 0.0000
% Pfam domain 3.935 3.7704 0.0307 0.0001 0.1290 0.0001 0.0001 0.0000 0.0046 0.0000 0.0000 0.0000
Exon feature category Subtotal
Structural-functional features 12.107 11.561 0.289 0.019 0.192 0.003 0.001 0.002 0.040 0.000 0.000 0.000
exon length 2.583 2.188 0.328 0.002 0.010 0.051 0.000 0.001 0.001 0.001 0.000 0.000
expression level 2.082 1.504 0.518 0.001 0.000 0.058 0.000 0.000 0.000 0.000 0.000 0.000
Compactness features 0.621 0.418 0.006 0.182 0.001 0.001 0.001 0.005 0.000 0.002 0.005 0.000
Other features 0.410 0.165 0.127 0.059 0.003 0.007 0.000 0.042 0.001 0.006 0.000 0.000
Splicing features 0.169 0.105 0.001 0.003 0.000 0.000 0.057 0.000 0.000 0.000 0.000 0.003