Table 1.
Comparison of definitions of the metabolic syndrome.
WHO | EGIR | NCEP | IDF |
---|---|---|---|
Presence of one of the following: | Insulin resistance AND two or more of the following: | Presence of three of the following (2001): | Central obesity(13) AND any two of the following: |
(i) DM | (i) Central obesity(4) | (i) Central obesity(6) | (i) Raised TG(14) |
(ii) IGT | (ii) Dyslipidemia(5) | (ii) Dislipidemia(7) | (ii) ↓ HDL(15) |
(iii) IFG | (iii) BP ≥ 140/90 | (iii) BP ≥ 130/85 | (iii) ↑ BP(16) |
(iv) Insulin resistance | (iv) FBG ≥ 6.1 mmol/L (110 mg/dL) | (iv) FPG ≥ 6.1 mmol/L (110 mg/dL) | (iv) ↑ FBG(17) |
AND two of the following: | Update (2004): | ||
(i) BP ≥ 140/90 | (i) Elevated waist circumferences(8) | ||
(ii) Dyslipidemia(1) | (ii) Elevated TG(9) | ||
(iii) Central obesity(2) | (iii) Reduced HDL(10) | ||
(iv) Microalbuminuria(3) | (iv) Elevated BP(11) | ||
(v) Elevated fasting glucose(12) |
BP: blood pressure, DM: diabetes mellitus, EGIR: European Group for the Study of Insulin Resistance, FBG: fasting blood glucose, HDL: high density lipoproteins, IDF: International Diabetes Federation, IFG: impaired fasting glucose, IGT: impaired glucose tolerance, NCEP: US National Cholesterol Education Program, TG: triglycerides, WHO: World Health Organization.
(1)TG ≥ 1.695 mmol/L and HDL ≤ 0.9 mmol/L (male), ≤1.0 mmol/L (female).
(2)Waist/hip ratio > 0.90 (male) >0.85 (female), or body mass index > 30 kg/m2.
(3)Urinary albumin excretion ratio ≥ 20 μg/min or albumin/creatinine ratio ≥ 30 mg/g.
(4)Waist circumference ≥ 94 cm (male), ≥80 cm (female).
(5)TG ≥ 2.0 mmol/L and/or HDL < 1.0 mmol/L or treated for dyslipidemia.
(6)Waist circumference ≥ 102 cm or 40 inches (male), ≥88 cm or 36 inches (female).
(7)TG ≥ 1.7 mmol/L (150 mg/dL) and HDL < 40 mg/dL (male), <50 mg/dL (female).
(8)Men, greater than 40 inches (102 cm) and women, greater than 35 inches (88 cm).
(9)Equal to or greater than 150 mg/dL (1.7 mmol/L).
(10)Men, Less than 40 mg/dL (1.03 mmol/L) and women, Less than 50 mg/dL (1.29 mmol/L).
(11)Equal to or greater than 130/85 mm Hg or use of medication for hypertension.
(12)Equal to or greater than 100 mg/dL (5.6 mmol/L) or use of medication for hyperglycemia.
(13)Defined as waist circumference with ethnicity specific values (If BMI is >30 kg/m², central obesity can be assumed and waist circumference does not need to be measured).
(14)TG > 150 mg/dL (1.7 mmol/L), or specific treatment for this lipid abnormality.
(15)HDL < 40 mg/dL (1.03 mmol/L) in males, <50 mg/dL (1.29 mmol/L) in females, or specific treatment for this lipid abnormality.
(16)systolic BP > 130 or diastolic BP > 85 mm Hg, or treatment of previously diagnosed hypertension.
(17)FPG > 100 mg/dL (5.6 mmol/L), or previously diagnosed type 2 diabetes.