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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Pharmacogenomics. 2011 Oct;12(10):1407–1415. doi: 10.2217/pgs.11.92

Table 1.

Drugs used in this study

Drug name Mechanism of action
Cladribine Ribonucleotide reductase inhibitor
Fludarabine Ribonucleotide reductase inhibitor
Gemcitabine Ribonucleotide reductase inhibitor
Azacitidine Ribonucleotide reductase inhibitor
Cytarabine Ribonucleotide reductase inhibitor
5-fluorouracil Thymidylate synthase inhibitor
Floxuridine Thymidylate synthase inhibitor
Epirubicin DNA intercalators and topoisomerase 2 inhibitors
Doxorubicin DNA intercalators and topoisomerase 2 inhibitors
Daunorubicin DNA intercalators and topoisomerase 2 inhibitors
Idarubicin DNA intercalators and topoisomerase 2 inhibitors
Mitoxantrone DNA intercalators and topoisomerase 2 inhibitors
Vincristine Microtubule destabilizers
Vinorelbine Microtubule destabilizers
Vinblastine Microtubule destabilizers
Docetaxel Microtubule stabilizers
Paclitaxel Microtubule stabilizers
Oxaliplatin DNA crosslinkers
Carboplatin DNA crosslinkers
Etoposide Topoisomerase 2 inhibitors
Teniposide Topoisomerase 2 inhibitors
Arsenic trioxide Other
Bleomycin Other
Busulfan Other
Hydroxyurea Other
Mitomycin Other
Rapamycin Other
Temozolomide Other
Topotecan Other