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Effect of cold-separation stress on CRH-mRNA in the paraventricular nucleus of 6-(panel A) and 9-(panel B) day-old rats. Pups were subjected to age-appropriate maximal tolerated cold-stress. CRH-mRNA was determined using in situ hybridization. Values (mean ± SEM) were derived as detailed in the Methods section. *Significantly different from control (p < 0.05).
