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. Author manuscript; available in PMC: 2012 Jul 18.
Published in final edited form as: Bioorg Med Chem. 2011 Mar 12;19(8):2589–2595. doi: 10.1016/j.bmc.2011.03.012

Figure 4.

Figure 4

Analyzes of inhibitor activity on ssDNA binding of RPA. RPA was incubated with compounds identified in the HTS (200 μM) and DNA binding of RPA was analyzed by EMSA. The position of free DNA and the RPA–DNA complex is denoted. Compounds labeled with red text inhibited RPA–DNA binding and were excluded from further study.